Book of the month: Genetically Engineered Mice Handbook
Genetically Engineered Mice Handbook by John P Sundberg and Tsutomu Ichiki.
Mice are today’s lab animal model of choice, in part because of their suitability for genetic engineering. To share information on the pathology of mice with spontaneous or genetically engineered mutations, prominent researchers organized a series of meetings. This book grew from those meetings, offering an introduction to this area of research and serving as a resource for those currently using mice as laboratory models. With contributions from nearly 60 leading researchers, the text presents systematic approaches for analyzing mutant mice for specific medical applications, details a variety of methods for creating mutants and includes information that is particularly hard to access dealing with legal responsibilities. It also covers the use of models for developmental biology and the monitoring of laboratory colonies. The book suggests what are the best public websites, and offers instruction on how to use them.
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